Noun

• S: (n) disability, disablement, handicap, impairment (the condition of being unable to perform as a consequence of physical or mental unfitness) "reading disability"; "hearing impairment"
• S: (n) handicap (advantage given to a competitor to equalize chances of winning)
• S: (n) hindrance, hinderance, deterrent, impediment, balk, baulk, check, handicap (something immaterial that interferes with or delays action or progress)

Verb

• S: (v) disable, invalid, incapacitate, handicap (injure permanently) "He was disabled in a car accident"
• S: (v) handicap (attempt to forecast the winner (especially in a horse race) and assign odds for or against a contestant)
• direct hypernym / inherited hypernym / sister term
• S: (v) bias (influence in an unfair way) "you are biasing my choice by telling me yours"
• S: (v) prejudice, prepossess (influence (somebody's) opinion in advance)
• S: (v) influence, act upon, work (have and exert influence or effect) "The artist's work influenced the young painter"; "She worked on her friends to support the political candidate"
• S: (v) affect, impact, bear upon, bear on, touch on, touch (have an effect upon) "Will the new rules affect me?"
• S: (v) change, alter, modify (cause to change; make different; cause a transformation) "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
• derivationally related form
• sentence frame
• Somebody ----s something
• Somebody ----s somebody
• Something ----s somebody
• Something ----s something
• S: (v) handicap, hinder, hamper (put at a disadvantage) "The brace I have to wear is hindering my movements"