S: (n) destiny, fate (the ultimate agency regarded as predetermining the course of events (often personified as a woman)) "we are helpless in the face of destiny"
S: (n) fortune, destiny, fate, luck, lot, circumstances, portion (your overall circumstances or condition in life (including everything that happens to you)) "whatever my fortune may be"; "deserved a better fate"; "has a happy lot"; "the luck of the Irish"; "a victim of circumstances"; "success that was her portion"
S: (n) misery, wretchedness, miserableness (a state of ill-being due to affliction or misfortune) "the misery and wretchedness of those slums is intolerable"
S: (n) catastrophe, disaster (a state of extreme (usually irremediable) ruin and misfortune) "lack of funds has resulted in a catastrophe for our school system"; "his policies were a disaster"
S: (n) extremity (an extreme condition or state (especially of adversity or disease))
S: (n) bitter end (the final extremity (however unpleasant it may be)) "he was determined to fight to the bitter end"
S: (n) distress (a state of adversity (danger or affliction or need)) "a ship in distress"; "she was the classic maiden in distress"
S: (n) pressure (an oppressive condition of physical or mental or social or economic distress)
S: (n) throe (hard or painful trouble or struggle) "a country in the throes of economic collapse"
S: (n) affliction (a state of great suffering and distress due to adversity)
S: (n) cross, crown of thorns (any affliction that causes great suffering) "that is his cross to bear"; "he bears his afflictions like a crown of thorns"
S: (n) victimization (adversity resulting from being made a victim) "his victimization infuriated him"
S: (n) gutter, sewer, toilet (misfortune resulting in lost effort or money) "his career was in the gutter"; "all that work went down the sewer"; "pensions are in the toilet"
S: (n) dead duck (something doomed to failure) "he finally admitted that the legislation was a dead duck"; "the idea of another TV channel is now a dead duck"; "as theories go, that's a dead duck"