S: (n) decimation (destroying or killing a large part of the population (literally every tenth person as chosen by lot))
S: (n) self-destruction (the act of destroying yourself) "his insistence was pure self-destruction"
S: (n) neutralization, neutralisation ((euphemism) the removal of a threat by killing or destroying it (especially in a covert operation or military operation))
S: (n) sabotage (a deliberate act of destruction or disruption in which equipment is damaged)
S: (n) change of state (the act of changing something into something different in essential characteristics)
S: (n) change (the action of changing something) "the change of government had no impact on the economy"; "his change on abortion cost him the election"
S: (n) action (something done (usually as opposed to something said)) "there were stories of murders and other unnatural actions"